Geneva, Jan 5th – The World Health Organization (WHO) announced the approval of the first conjugate vaccine against typhoid fever suitable for children over six months in countries where the disease is endemic.
The new immunogen, Typbar-TCV, meets the standards of quality, safety and efficacy, which makes it eligible to be acquired by UN agencies such as UNICEF and GAVI, the Global Alliance for Vaccines, said on Wednesday the UN agency said in a statement.
According to the agency, conjugate vaccines against typhoid fever (TCV) are innovative products that generate an immunity that is longer than the older ones, require fewer doses and can be administered to young children through routine immunization programs.
Also its use should help to curb the frequent use of antibiotics in the treatment of this evil, and thus help to slow down the alarming increase in resistance to those drugs against the bacteria Salmonella Typhi, which causes the disease, he adds.
For this reason, the adoption by the organization is a crucial step necessary for the vaccine is available in low- and middle-income countries, where they need it most, explained the agency in the note.
Who gives this step after the group of experts of strategic advice on immunization, which advises the World Health Organization (WHO), recommends in October of 2017 the TCV for routine use in children older than six months in countries where typhoid fever is endemic.
It also requested the introduction of the conjugate vaccine on a priority basis in countries with the highest rates of typhoid fever or antibiotic resistance of Salmonella Typhi, after the recommendation of the Group, the Board of GAVI, the Global Alliance for Vaccines, approved a financing of 85 million dollars to enter 2019 in the immunogen TCV of Bharat Biotech.
Other vaccines, such as the Viva Ty21a oral and injectable Vi polysaccharide are internationally approved for human beings, but only from the age of two years.
Typhoid fever is a serious infection and sometimes fatal disease that is contracted through contaminated food or water, which causes fever, fatigue, headache, stomach ache, diarrhea and colds.
Each year there are between 11 and 20 million cases and between 128 thousand and 161 thousand deaths in low- and middle-income countries.